Medical diagnostics
Transforming medical diagnostics with exceptional sensitivity
Medical diagnostics is about to be transformed – saving lives and money. Canatu CNT offers the highest sensitivity outside a lab – over 10 times more sensitive than anything our competitors can offer. Proven in in vitro matrices, the superior sensitivity is made possible by our patented dry deposition™ technology, which allows us to create CNTs with uniquely pristine and expansive surface areas. This enormous, three-dimensional surface provides many binding sites for biorecognition elements to interact with target analytes, enabling stronger signals even in complex matrices. Exceptional sensitivity unlocks unprecedented detection capabilities for new assays. Furthermore, severe infections and diseases, like cancer, can now be diagnosed at their earliest stages, improving patient outcomes, monitoring, and safety.
Industry trends
- Early detection of diseases
- Point-of-care testing
- Specialized disease-specific biomarkers
Canatu biosensors
- Sensitive: >10x higher sensitivity in in vitro matrices
- Versatile: platform technology for detecting any analyte of interest
- At scale: experience and expertise to produce tens of millions of sensors annually
Our products
Electrochemical biosensors offer the highest sensitivity outside a lab – over ten times more sensitive than anything our competitors can offer. Exceptional sensitivity unlocks unprecedented opportunity to detect new assays, as well as severe diseases and infections, at their earliest stages.
Electrochemical sensors offer unparalleled detection capabilities across industries. Their superior sensitivity allows detection of substances at extremely low concentrations, making them indispensable for on-site monitoring of critical parameters in medical diagnostics, veterinary care, environmental monitoring, food & beverages, and industrial processes. Discover our future developments.
Watch video on biosensors for medical diagnostics
Lab in hand enables informed decisions at point-of-care
Medical diagnostics is on the verge of something new. Testing is shifting from centralized to point-of-care, enabling simple testing and quick results in minutes. Electrochemical biosensors are at the forefront of this transformation. They provide quantitative detection of any desired analyte at the point of care. Multiple biomarkers can be tested simultaneously. This empowers caregivers to make better-informed decisions at the point-of-care, saving lives and money.
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We are looking to partner with frontrunners ready to transform medical diagnostics at the point of care. Download technical data to explore our capabilities further.
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We partner with forerunners ready to transform industries
Our latest research with ecosystem partners and academia:
Introduction of an electrochemical point-of-care assay for quantitative determination of paracetamol in finger-prick capillary whole blood samples
Kujala, J.; Wester, N.; Lohela, T. J.; Kurkela, M.; Backman, J.T.; Mikladal B.; Laurila, T.; Koskinen, J.; Lilus, T. O.; Kalso, E. A., British Journal of Clinical Pharmacology, 89(9), 2933-2938 (2023)
The paracetamol capillary blood concentrations measured with the novel electrochemical ‘point-of-care’ method correlate with the ‘gold standard’ HPLC-MS/MS method in capillary blood.
Rapid industrial scale synthesis of robust carbon nanotube network electrodes for electroanalysis
Leppänen, E et al. Journal of Electroanalytical Chemistry, vol. 896 (2021)
Canatu electrochemical sensors can be produced at industrial scale and reproducibility. We also have the possibility to modify CNT deposition process parameters to alter the electrochemical response, as was demonstrated in this article. These results provide a proof-of-principle that both the sensitivity and selectivity towards analytes-of-interest can be modified by altering the morphology of the SWCNT network.
Real-time selective detection of dopamine and serotonin at nanomolar concentration from complex in vitro systems
Rantataro, S et al. Biosensors and Bioelectronics 115579 (2023)
Canatu SWCNT electrodes show outstanding analytical performance, being capable of simultaneously detecting dopamine and serotonin at nanomolar concentration in the highly fouling culture medium. Analytical performance of our SWCNT electrodes in culture medium is comparable to the performance of other state-of-the-art electrodes in highly clean phosphate buffer, which lacks all the fouling components present in culture medium. Perhaps most importantly, this state-of-the-art analytical performance can now be finally obtained at industrial scale and reproducibility.
The Canatu SWCNT electrodes also demonstrate excellent biocompatibility, as they were able to sustain healthy development of primary midbrain dopaminergic neuron culture. Because of the unique combination of excellent analytical performance and biocompatibility, Canatu SWCNTs are currently the only material capable of being integrated into brain-on-a-chip devices. Furthermore, they could be used for the monitoring of complex in vitro models to facilitate drug discovery and development.
Ascorbic acid does not necessarily interfere with the electrochemical detection of dopamine
Rantataro, S. et al. Sci Rep 12, 20225 (2022)
Electrochemical detection of neurotransmitters is severely complicated by the presence of ascorbic acid. However, this challenge can be eliminated through experimental design in vitro. By utilizing the highly sensitive Canatu SWCNTs, nanomolar detection of dopamine was demonstrated for the first time, as measured directly from the cell culture medium in the presence of ascorbic acid at initially high concentration.
Electrochemical Detection of Oxycodone and Its Main Metabolites with Nafion-Coated Single-Walled Carbon Nanotube Electrodes
Mynttinen, E et al. Analytical Chemistry 92 (12), 8218-8227 (2022)
We developed a disposable, mass-producible Nafion-coated single-walled carbon nanotube sensor and demonstrated, for the first time, selective detection of oxycodone in the presence of its two major metabolites.
Disposable Nafion-Coated Single-Walled Carbon Nanotube Test Strip for Electrochemical Quantitative Determination of Acetaminophen in a Finger-Prick Whole Blood Sample
Wester, N et al. Analytical Chemistry 92 (19), 13017-13024 (2020)
Our mass-production compatible fabrication process has also been used to develop a quantitative point-of-care sensor for the determination of acetaminophen within the clinically relevant concentration range.
Electrochemical Detection of Morphine in Untreated Human Capillary Whole Blood
Verrinder, E et al. ACS Omega 6 (17), 11563-11569 (2021)
In this work, we demonstrated quantitative electrochemical detection of clinically relevant concentrations of morphine in undiluted and untreated capillary whole blood.
Effect of Electrochemical Oxidation on Physicochemical Properties of Fe-Containing Single-Walled Carbon Nanotubes
Verrinder, E et al. ChemElectroChem 6 (17), 11563-11569 (2021)
In this article, we studied how the Fe-nanoparticle oxidation state affects analytical performance of our SWCNT electrodes. Whereas sensitivity towards the detection of analgesics was only marginally affected by the oxidation state, selectivity between paracetamol and morphine could be improved by electrochemical pre-treatment.
Contact our specialist in medical diagnostics
Send us a message
We are looking to partner with frontrunners ready to transform medical diagnostics at the point of care. If you’re interested in exploring this opportunity further, contact our CTO Ilkka Varjos.
Related content
While our experts solve the issues of today, they are also working on what’s to come. Currently, our technology for electrochemical sensors is developing fast. Because of the exceptional purity of Canatu CNTs, remarkable analytical performance can be attained in various sectors such as clinical analysis, environmental monitoring, agriculture and neuroscience. Learn more.
The inherently large surface area, high conductivity and tailorable surface chemistry makes Canatu CNT an ideal electrode material for electrochemical sensors. See the product.
Electrochemical sensors for bedside blood concentration measurement progress to clinical studies. The new point-of-use measurement enables real-time detection of analgesics from blood without extensive sample treatment, improving test result wait time, cost and convenience. See press release.
Finnish ecosystem spurs diagnostics development. Canatu will develop a new hybrid electrochemical sensor for target detection and drug concentration measurement. See press release.
Canatu creates nano solutions for massive impact. We work with carbon, the most versatile material in the universe, and collaborate with other forerunner companies to make breakthrough innovations. See our company.
Canatu partners with forerunner companies, research partners and a leading Finnish University Hospital, together transforming products for better tomorrows with nano carbon. See how we collaborate for an impact.
